A Novel Distributed Privacy Paradigm for Visual Sensor Networks Based on Sharing Dynamical Systems

Visual sensor networks (VSNs) provide surveillance images/video which must be protected from eavesdropping and tampering en route to the base station. In the spirit of sensor networks, we propose a novel paradigm for securing privacy and confidentiality in a distributed manner. Our paradigm is based on the control of dynamical systems, which we show is well suited for VSNs due to its low complexity in terms of processing and communication, while achieving robustness to both unintentional noise and intentional attacks as long as a small subset of nodes are affected. We also present a low complexity algorithm called TANGRAM to demonstrate the feasibility of applying our novel paradigm to VSNs. We present and discuss simulation results of TANGRAM

Distributed secrecy for information theoretic sensor network models

This dissertation presents a novel problem inspired by the characteristics of sensor networks. The basic setup through-out the dissertation is that a set of sensor nodes encipher their data without collaboration and without any prior shared secret materials. The challenge is dealt by an eavesdropper who intercepts a subset of the enciphered data and wishes to gain knowledge of the uncoded data. This problem is challenging and novel given that the eavesdropper is assumed to know everything, including secret cryptographic keys used by both the encoders and decoders. We study the above problem using information theoretic models as a necessary first step towards an understanding of the characteristics of this system problem. This dissertation contains four parts. The first part deals with noiseless channels, and the goal is for sensor nodes to both source code and encipher their data. We derive inner and outer regions of the capacity region (i.e the set of all source coding and equivocation rates) for this problem under general distortion constraints. The main conclusion in this part is that unconditional secrecy is unachievable unless the distortion is maximal, rendering the data useless. In the second part we thus provide a practical coding scheme based on distributed source coding using syndromes (DISCUS) that provides secrecy beyond the equivocation measure, i.e. secrecy on each symbol in the message. The third part deals with discrete memoryless channels, and the goal is for sensor nodes to both channel code and encipher their data. We derive inner and outer regions to the secrecy capacity region, i.e. the set of all channel coding rates that achieve (weak) unconditional secrecy. The main conclusion in this part is that interference allows (weak) unconditional secrecy to be achieved in contrast with the first part of this dissertation. The fourth part deals with wireless channels with fading and additive Gaussian noise. We derive a general outer region and an inner region based on an equal SNR assumption, and show that the two are partially tight when the maximum available user powers are admissible

CASE REPORT: HEMICHOREA-HEMIBALLISMUS IN NON-KETOTIC HYPERGLYCEMIA AND NON-HEMORRHAGIC STROKE PATIENT WITH BASAL GANGLIA HYPERDENSITY

Background : Hemichorea-hemiballismus (HC-HB) is a hyperkinetic disorder characterized by uncontrolled movements, non patterned, occurring mostly in the proximal extremity on one side of the body. The etiology that most often causes HC-HB is acute cerebrovascular disorder. Non-ketotic hyperglycemia is another etiology that is very important because it is the second most common cause of HC-HB and can be manifested as an initial symptom or complication of diabetes mellitus. This case is rare and the prevalence is unknown. Case : A diabetic patient with non-ketotic hyperglycemia reported  with hemiballismus syndrome. A 60-year-old woman experiences involuntary, repetitive, and non-rhythmic movements in the left arm and leg. These patients have a history of uncontrolled diabetes mellitus and hypertension. Head CT scan images in patients showed hyperdensity lesions in the right basal ganglia which were thought to be caused by non-ketotic hyperglycemia and infarction in the right temporal lobe. Involuntary movements improve after blood glucose targets are achieved by administering basal and prandial insulin.  Clinical response in the case of hemiballismus above is reversible even though the appearance of hyperdensityt lesions can last for several months. Discussion : Hemichorea-Hemiballismus (HC-HB) is a rare disorder of involuntary movement, most often caused by focal lesions in the basal ganglia and the contralateral subthalamic nucleus. HC-HB is mainly caused by systemic processes both focal and diffuse. Nonketotic hyperglycemia is known to be a metabolic cause of HC-HB, especially in elderly patients with uncontrolled diabetes mellitus. Clinical manifestations and supporting patients support hyperglycemia and basal ganglia hyperdensity to be the etiology of hemiballismus experienced by patients. Conclusion : Many etiologies can cause this disorder, but vascular disorders and non-ketotic hyperglycemia are the most common etiologies. HC-HB in non-ketotic hyperglycemic is manifestation which is very rare in diabetes mellitus. The prognosis is quite good in most patients with or without treatment. This case report describes a successful treatment approach with positive results and a fairly short duration. Keywords: Hemichorea, Hemiballismus, Hyperglycemia, Basal Ganglia Hyperdensit

Collusion-resistant fingerprinting for multimedia in a broadcast channel environment

Digital fingerprinting is a method by which a copyright owner can uniquely embed a buyer-dependent, inconspicuous serial number (representing the fingerprint) into every copy of digital data that is legally sold. The buyer of a legal copy is then deterred from distributing further copies, because the unique fingerprint can be used to trace back the origin of the piracy. The major challenge in fingerprinting is collusion, an attack in which a coalition of pirates compare several of their uniquely fingerprinted copies for the purpose of detecting and removing the fingerprints. The objectives of this work are two-fold. First, we investigate the need for robustness against large coalitions of pirates by introducing the concept of a malicious distributor that has been overlooked in prior work. A novel fingerprinting code that has superior codeword length in comparison to existing work under this novel malicious distributor scenario is developed. In addition, ideas presented in the proposed fingerprinting design can easily be applied to existing fingerprinting schemes, making them more robust to collusion attacks. Second, a new framework termed Joint Source Fingerprinting that integrates the processes of watermarking and codebook design is introduced. The need for this new paradigm is motivated by the fact that existing fingerprinting methods result in a perceptually undistorted multimedia after collusion is applied. In contrast, the new paradigm equates the process of collusion amongst a coalition of pirates, to degrading the perceptual characteristics, and hence commercial value of the multimedia in question. Thus by enforcing that the process of collusion diminishes the commercial value of the content, the pirates are deterred from attacking the fingerprints. A fingerprinting algorithm for video as well as an efficient means of broadcasting or distributing fingerprinted video is also presented. Simulation results are provided to verify our theoretical and empirical observations

Phase 2 Study of Anti-Human Cytomegalovirus Monoclonal Antibodies for Prophylaxis in Hematopoietic Cell Transplantation.

Human cytomegalovirus (HCMV) can cause significant disease in immunocompromised patients, and treatment options are limited by toxicities. CSJ148 is a combination of two anti-HCMV human monoclonal antibodies (LJP538 and LJP539) that bind to and inhibit the functions of viral HCMV glycoprotein B (gB) and the pentameric complex, consisting of glycoproteins gH, gL, UL128, UL130, and UL131. In this phase 2, randomized, placebo-controlled trial, we evaluated the safety and efficacy of CSJ148 for prophylaxis of HCMV in patients undergoing allogeneic hematopoietic stem cell transplantation. As would be expected in the study population, all the patients (100%) reported at least one treatment-emergent adverse event. There were 22 deaths during this study, and over 80% of the patients receiving placebo or CSJ148 developed at least one adverse event of grade 3 or higher severity. No subject who received antibody developed a hypersensitivity- or infusion-related reaction. CSJ148-treated patients showed trends toward decreased viral load, shorter median duration of preemptive therapy, and fewer courses of preemptive therapy. However, the estimated probability that CSJ148 decreases the need for preemptive therapy compared to placebo was 69%, with a risk ratio of 0.89 and a 90% credible interval of 0.61 to 1.31. The primary efficacy endpoint was therefore not met, indicating that CSJ148 did not prevent clinically significant HCMV reactivation in recipients of allogeneic hematopoietic cell transplants. (This study has been registered at ClinicalTrials.gov under identifier NCT02268526 and at EudraCT under number 2017-002047-15.)

Peningkatan Pengetahuan Warga Rusun X untuk Menurunkan Perilaku Merokok Menggunakan Kerangka Theory of Planned Behavior (TPB)

Hampir 90% warga laki-laki Rusun X Surabaya merupakan perokok aktif. Berdasarkan hasil wawancara, warga menilai efek yang diberikan merokok salah satunya adalah bisa menjadi sebuah media dalam bersosialisasi. Berawal dari adanya keinginan warga untuk mengurangi perilaku merokok, peneliti menggunakan kerangka kerja theory of planned behavior untuk memberikan intervensi perubahan perilaku pada warga Rusun X. Intervensi yang dilakukan berupa penyuluhan yang bertujuan meningkatkan pengetahuan untuk menurunkan perilaku merokok melalui penyuluhan. Partisipan penyuluhan ini dilakukan pada warga perokok aktif laki-laki di Rusun X Surabaya berjumlah 15 orang. Berdasarkan hasil penelitian, adanya peningkatan pengetahuan terkait dengan perilaku merokok sehingga berdampak pada perubahan sikap dan perilaku. Partisipan yang mengalami perubahan perilaku ini telah memiliki niatan untuk mengubah perilaku dan selanjutnya akan membantu menyebarkan informasi terkait dengan bahaya merokok kepada warga sekitar. Kata Kunci: permasalahan komunitas,penyuluhan, perilaku merokok, theory of planned behavio

Novel Common Genetic Susceptibility Loci for Colorectal Cancer

BACKGROUND: Previous genome-wide association studies (GWAS) have identified 42 loci (P < 5 × 10-8) associated with risk of colorectal cancer (CRC). Expanded consortium efforts facilitating the discovery of additional susceptibility loci may capture unexplained familial risk. METHODS: We conducted a GWAS in European descent CRC cases and control subjects using a discovery-replication design, followed by examination of novel findings in a multiethnic sample (cumulative n = 163 315). In the discovery stage (36 948 case subjects/30 864 control subjects), we identified genetic variants with a minor allele frequency of 1% or greater associated with risk of CRC using logistic regression followed by a fixed-effects inverse variance weighted meta-analysis. All novel independent variants reaching genome-wide statistical significance (two-sided P < 5 × 10-8) were tested for replication in separate European ancestry samples (12 952 case subjects/48 383 control subjects). Next, we examined the generalizability of discovered variants in East Asians, African Americans, and Hispanics (12 085 case subjects/22 083 control subjects). Finally, we examined the contributions of novel risk variants to familial relative risk and examined the prediction capabilities of a polygenic risk score. All statistical tests were two-sided. RESULTS: The discovery GWAS identified 11 variants associated with CRC at P < 5 × 10-8, of which nine (at 4q22.2/5p15.33/5p13.1/6p21.31/6p12.1/10q11.23/12q24.21/16q24.1/20q13.13) independently replicated at a P value of less than .05. Multiethnic follow-up supported the generalizability of discovery findings. These results demonstrated a 14.7% increase in familial relative risk explained by common risk alleles from 10.3% (95% confidence interval [CI] = 7.9% to 13.7%; known variants) to 11.9% (95% CI = 9.2% to 15.5%; known and novel variants). A polygenic risk score identified 4.3% of the population at an odds ratio for developing CRC of at least 2.0. CONCLUSIONS: This study provides insight into the architecture of common genetic variation contributing to CRC etiology and improves risk prediction for individualized screenin